diff --git a/Formula/openssl.rb b/Formula/openssl.rb
index ec4d87ff570..d53b8196b44 100644
--- a/Formula/openssl.rb
+++ b/Formula/openssl.rb
@@ -12,6 +12,8 @@ class Openssl < Formula
     sha1 "4fabb39f5db46e8e62bf0b05e0133cd7e717860a" => :lion
   end
 
+  depends_on "makedepend" => :build if MacOS.prefer_64_bit?
+
   keg_only :provided_by_osx,
     "The OpenSSL provided by OS X is too old for some software."
 
@@ -31,9 +33,6 @@ class Openssl < Formula
       inreplace 'Configure',
         %{"darwin64-x86_64-cc","cc:-arch x86_64 -O3},
         %{"darwin64-x86_64-cc","cc:-arch x86_64 -Os}
-
-      inreplace "util/domd", %{expr "$MAKEDEPEND" : '.*gcc$' > /dev/null}, %{true}
-      inreplace "util/domd", %{${MAKEDEPEND}}, ENV.cc
     else
       args << "darwin-i386-cc"
     end